It’s possible for a person with sickle cell disease or sickle cell trait to have a baby born with sickle cell disease. But it also depends on the genes of the other parent.
How Does a Baby Get Sickle Cell Disease?
Every baby is born with two copies of the beta globin gene. They get one copy from each parent. Each copy can be normal or changed (mutated). A changed gene is called a variant.
There are different types of beta globin gene variants. One type is called a sickle cell variant.
If a baby gets two beta globin gene variants and at least one of them is the sickle cell variant, the baby will have sickle cell disease.
How Does Someone Get Sickle Cell Disease?
Sickle cell disease is genetic. That means it gets passed down in genes from parents to kids. Find out how it happens.
How Can I Learn My Sickle Cell Status?
To know your status means finding out if you have a beta globin gene variant, and the type. A simple blood test can tell you.
It’s best for both partners to know their status before they have kids.
What if Both Partners Have a Beta Globin Gene Variant?
When both partners have a beta globin gene variant, it’s a good idea to talk with a genetic counselor. These counselors have special training in genetics and can help people decide what is right for them. They can tell you about your chances of having a child with sickle cell disease. They also can explain your options for having kids when you’re ready.
Date reviewed: January 2024
