Poor Sleep in Pregnancy Linked to Developmental Risks – Neuroscience News

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Summary: New research suggests that pregnant women who get less than seven hours of sleep per night may have a higher risk of having children with neurodevelopmental delays. The study, involving over 7,000 mother-child pairs, found that children of mothers with short sleep duration (SSD) were more likely to experience delays in cognitive, behavioral, and motor skills.

Boys appeared particularly vulnerable, and researchers also observed that glucose metabolism in mothers might affect fetal development. These findings emphasize the importance of managing sleep health during pregnancy to potentially reduce developmental risks.

Key Facts:

  • Sleep duration under seven hours during pregnancy is linked to a higher risk of neurodevelopmental delays in children.
  • Boys seem more susceptible to these delays when mothers experience SSD during pregnancy.
  • Poor maternal sleep may disrupt glucose metabolism, impacting fetal development and insulin secretion.

Source: The Endocrine Society

Pregnant women who do not get enough sleep may be at higher risk of having children with neurodevelopmental delays, according to new research published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

Short sleep duration (SSD) is defined as sleeping less than seven hours per night. Pregnant woman may have trouble sleeping due to hormonal changes, pregnancy discomfort, frequent urination, and other factors.

It’s been reported that almost 40% of pregnant women have SSD. These women may have a higher risk of impaired glucose tolerance, insulin resistance and gestational diabetes, and their children may be at higher risk of experiencing neurodevelopmental delays. These children are slower to develop their social, emotional, behavioral, motor, cognitive, or speech skills.

“This study highlights the necessity of managing sleep health during pregnancy.

“By shedding light on the connection between maternal sleep during pregnancy and children’s neurodevelopment, our study empowers families with knowledge that can shape healthier pregnancy habits and contribute to the well-being of the next generation,” said lead study author Peng Zhu, M.D., of Anhui Medical University and the MOE Key Laboratory of Population Health Across Life Cycle in Hefei, China.

“Improving sleep habits during pregnancy may prevent or reduce the risk of neurodevelopmental issues in children.”

The researchers analyzed sleep data from 7,059 mother-child pairs from 3 different hospitals in China. They screened the children for developmental delays from 6 months to 3 years old and analyzed the link between maternal sleep duration and neurodevelopmental delay risk.

They also evaluated the role of cord blood serum C-peptide levels, which are a stable indicator of fetal insulin secretion.

The study found: 

  • Insufficient sleep during pregnancy may be associated with an increased risk of neurodevelopmental issues in children, affecting their cognitive abilities, behavioral development and learning capabilities.
  • Boys appear to be at a higher risk of neurodevelopmental delays when their mothers experience SSD during pregnancy, suggesting that gender plays a crucial role in offspring response to prenatal environmental factors.
  • SSD during pregnancy might affect the mother’s glucose metabolism, thereby influencing the fetal development environment.
  • There may be a positive correlation between C-peptide levels in umbilical cord blood and neurodevelopmental delays in offspring, indicating that a mother’s glucose metabolism during pregnancy may impact the insulin secretion of the fetus and, consequently, their neurodevelopment.

“Prenatal health is important not only for the expectant mother but also for the long-term health of the unborn child,” said Zhu.

Other study authors include: Lei Zhang, Hai-Xia Wang, Yuan-Yuan Zhu, Rui-Rui Ma, and Yu-Hong Wang of Anhui Medical University and the MOE Key Laboratory of Population Health Across Life Cycle; Wen-Xiang Li of Anhui Medical University; and Yu Zhang and Dao-Min Zhu of the Affiliated Psychological Hospital of Anhui Medical University, the Hefei Fourth People’s Hospital and Anhui Mental Health Center in Hefei, China.

Funding: This research received financial support from the National Natural Science Foundation of China, the Innovative Research Group Project of the National Natural Science Foundation of China, the National Key R&D Program of China, the Research Funds of Center for Big Data and Population Health of IHM, and the Foundation for Scientific Research Improvement of Anhui Medical University.

About this sleep and neurodevelopment research news

Author: Colleen Williams
Source: The Endocrine Society
Contact: Colleen Williams – The Endocrine Society
Image: The image is credited to Neuroscience News

Original Research: The findings will appear in The Journal of Clinical Endocrinology & Metabolism

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